2016_Head & Neck COURSE BOOK

FUTURE TRENDS Clinical activity of androgen deprivation therapy in patients with metastatic/relapsed ARpositive salivary gland cancers L. Locati, F. Perrone, B. Cortelazzi, S. Lo Vullo, P. Bossi, G. Dagrada, P. Quattrone, C. Bergamini, P. Potepan, E. Civelli, C. Fallai, S. Pilotti, L. Licitra Head & Neck 2015 17 pts with relapsing and/or metastatic SGCs AR-expressing: SDC (N=8), adenocarcinoma NOS (N=7), cystadenocarcinoma (N=1) and poorly differentiated carcinoma originated from SDC (N=1) All pts were homogeneously treated with ADT ( Bicalutamide + decapeptyl) No significant toxicities were reported. Overall response rate was 64.7%; three - year PFS and 5 - year OS were 11.8% and 19.3%, respectively

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