2016_Head & Neck COURSE BOOK

Salvage Surgery

FDG-PET

Problems: • <3-4 months after (C)RT high incidence equivocal and inaccurate interpretation (local and regional) • Problems: • False-positive: inflammatory effect • False-negative: tumors < 0.5 cm

Accuracy after (chemo)radiation for head and neck carcinoma:

Regional

Sensitivity

Specificity

Local

Sensitivity

Specificity

PET

40% - 100%

25% - 100%

PET

50% - 100%

64% - 93%

Negative predictive value at 3 months in general very reliable