2016_Head & Neck COURSE BOOK

Fractionation sensitivity

E l ar y reac ng norma ssues ti l ti

L t a e reac ng norma ssues ti l ti

• Low fractionation

• High fractionation

sensitivity

sensitivity

• Small increase in tolerance  with decreasing dose per  f i ract on

• Large increase in 

tolerance with decreasing d f i ose per ract on

• High alpha beta (8 30 Gy) ‐ ‐ 

• Low alpha beta (2 4 Gy) ‐ ‐ 

• Time factor (repopulation)

• No time factor