2016_Head & Neck COURSE BOOK

Fractionation sensitivity

Early reacting normal tissues

Late reacting normal tissues

• Low fractionation sensitivity

• High fractionation sensitivity

• Small increase in tolerance with decreasing dose per fraction

• Large increase in

tolerance with decreasing dose per fraction

• High alpha-beta (8-30 Gy)

• Low alpha-beta (2-4 Gy)

• Time factor (repopulation)

• No time factor