2016_Head & Neck COURSE BOOK

Sinonasal Tumor - HPV

Bishop JA; Am J Surg Pathol 2013 . Human papillomavirus-related carcinomas of the sinonasal tract

• 161 sinonasal carcinomas • 34 (21%) HPV Pos (28 SCC and variants) • 59 (37%) p16 IHC positive

• p16 expression strongly correlate with HPV DNA presence : • A trend toward improved survival was observed in the HPV- iti pos ve group

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