2016_Head & Neck COURSE BOOK

Integration sites of HPV16 in HNSCC

TP63: a member of the p53 family , tumor suppressor, decrease chemosensitivity

RAD51B: DNA damage repair , radiation sensitivity

Kruppel-like factor 5 (KLF5): zinc finger - - containing transcription factor, maintain pluripotency in stem cells

CD275 (PD-L1, B7-H1): Immune h k i t t i c ec po n pro e n

Joseph D. Khoury et al. J. Virol. 2013;87:8916-8926