2016 Hematological Malignancies

HD8: Long-term Outcome

OS

PFS

15 year estimate [95%-CI] EF: 72.7% [68.2% to 77.2%] IF: 73.8% [69.2% to 78.3%] diff: 1.1% [-5.3% to 7.5%] Hazard Ratio 0.98 [0.76 to 1.25] Median observation time 153 months

15 year estimate [95%-CI] EF: 80.5% [76.7% to 84.3%] IF: 82.4% [78.7% to 86.0%] diff: 1.8% [-3.4% to 7.1%] Hazard Ratio 0.88 [0.66 to 1.16] Median observation time 174 months

523

517

532

532

 No difference in 15-year PFS and OS between consolidative EF and IF-RT after 2x COPP/ABVD in early-stage unfavorable HL.

Bröckelmann et al; EHA 2016