2017_IGRT course book

Early Breast Cancer: S ± XRT meta-analysis Total: 40 Prosp. Rand. Trials, N ≈ 20,000 (50% had N+ve disease), XRT treating breast/chest wall, SCF, AX, IM regions

Increased mortality with XRT ! - 30% Cardeiac deaths

Difference = 4.8%

EBCT Collaborative Group. Lancet 2000

Radiotherapy