2017_IGRT course book

Radiotherapy in breast cancer: Heart Toxicity

Latency of 15-20 years

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• Myocardial scintigraphy can detect perfusion changes as early as 6 mo

Target structures: •

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Myocardium (e.g. left ventricle) • Vessels (e.g. left anterior descending coronary artery)

Toxicity •

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Myocardial infarction

Angina

• • •

CHF

Valvular disorders

• Electrical conductivity alterations

Dose threshold??

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03/01/13