2017 Imaging for Physicists Coursebook

The DCE-MRI experiment Initial T1 relaxation

−

with contrast agent

1

1

1

−

ℎ

1,0

=

+ 1

−

(Relaxivity)

1

1

1,0

−

Signal dependence on flip angle and T1

T1 = 200ms

T1 = 400ms

Make repeated measurements with different flip angles

Fit the equation and determine T1