2017 Imaging for Physicists Coursebook

1 i T T r C i       1 ,0 , i i

1, 2

1 i T T r C i       1 ,0 , i i

1, 2

Summary so far

Dynamic series gives clinically relevant information

Problem: without quantitative methods the results will be: 1. Dependent on scanner 2. Dependent on sequence 3. Dependent on coils 4. Etc.

Signal

Quantitative methods rely on determination of the contrast agent concentration Problem: This is not easy to determine 1. Unknown relaxivity 2. Complicated relation between concentration and signal 3. Inflow effects 4. Water exchange 5. Spoiling 6. Etc.

Time

C

Time