2017_SBRT_Course Book

Unresectable CRLM Local treatment

CRLM - colorectal liver metastases

• Phase II study in unresectable colorectal liver–limited metastases • Randomised to systemic treatment alone ( standard arm ) or systemic treatment plus local treatment by RFA +/- resection ( experimental arm - CMT ) • Primary end point: 30-month OS rate higher than 38% in CMT arm • 119 patients were randomized

Ruers T, JNCI 2017