2017_SBRT_Course Book

Factors influencing choice of ablative modality

Need for tissue (mutations, PDL1 expression, liquid biopsies) Location (brain, bone/vertebra, liver, liver hilus, central lung) Size of lesion (>3 cm cutoff) Previous treatments (high-dose radiation, surgery) Co-morbidities, patient preferences, institutional experience Timing (phased treatments, initial systemic therapy) Enhancement of immune function (SABR)

Senan S, ESMO 2017