2017_SBRT_Course Book

RT changes the diversity of T-cell receptors

Depletion of Treg (T cells which modulate the immune system, maintain tolerance to self-antigens, and abrogate autoimmune disease)

Altered expression of MHC-I and II

Activation of antigen presenting dendritic cells

Activation of cytotoxic T-cells (CD8 + )

Demaria et al. Front Oncol 2012; 2: 1-7