207_Combined course Presentations
RTOG 0617 – Conclusions
“ Positive” of RTOG 0617
• Excellent median survival of 28.7 months in the 60-Gy study arms when
compared with prior cooperative group studies in stage III NSCLC.
• May reflect PET scan use for staging (used in ~ 90% of pts)
“ Negative” of RTOG 0617
• 74 Gy radiation with concurrent CT was not better than 60 Gy for patients with
stage III NSCLC, and might be potentially harmful.
• Addition of Cetuximab to concurrent CR-RT and consolidation treatment
provided no benefit in OS for these patients, but increased overall grade 3-5
toxicity (85% vs 69%, p < 0.0001)
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