207_Combined course Presentations
The Oligometastatic State
In a 1995 JCO Editorial, clinical evidence led Hellmann and Weichselbaum to coin the term “oligometastases”
It was a proposal for a new clinical concept :
Intermediate biologic state of restricted metastatic capacity between truly locoregionally-confined and widely –metastatic cancer
Limited number and organ sites of metastases
Transitional state to dissemination (not yet achieved a widespread dissemination)
Oligometastatic state (by “arbitrary definition”): limited number of metastases ( usually ≤ 5 ), all amenable to radical local therapies
Weichselbaum & Hellmann. J Clin Oncol 1995;13 Weichselbaum & Hellmann. Nat Rev Clin Oncol 2011;8
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