207_Combined course Presentations

Time-to-events endpoints (38) As you can see there are many different time to event endpoints, with very subtle differences and different papers may even use different names for the same outcome:

Results from systematic review of RCTs of systemic therapy for EBC

DFS RFS EFS TTR Total

LR + DR + CLB + NBSP + Death

7

0

2

0

9

LR + DR + CLB + DCIS + Death

1

0

0

0

1

LR + DR + CLB + DCIS + BC Death

0

0

0

1

1

LR + DR + CLB + Death

3

0

0

0

3

LR + DR + CLB + NBSP

1

0

0

0

1

LR + DR + CLB

2

3

0

1

6

LR + DR + Death

6

1

1

1

9

LR + DR

3

3

0

1

7

LR + DR + BC Death

0

1

0

0

1

Table: Lucy S Kilburn Clinical Trials & Statistics Unit (ICR-CTSU), The Institute of Cancer Research, London, UK LR = local recurrence, DR =distant recurrence, CLB= contralateral breast, NBSP =National Breast Screening Programme