207_Combined course Presentations
Integrate pathology and biology
Histologic Grade
Low ( I of III)
Intermediate (II of III)
High (III of III)
Biomarkers
ER expression
+++
++ to +++
+ to ++
PR expression
++ to +++
0 to +++
0 to ++
Proliferation (Ki-67 / S phase fraction)
Low (<10%)
Intermediate (10-20%)
High (>20%)
HER2 Overexpression
Never
Occasional
Occasional
Genetic / Genomic / multipanel markers
21-gene recurrence score
Low (< 18)
Intermediate (18-25)
High ( >25)
Intrinsic subtype
Luminal A
Luminal B
Genomic Grade
Lower
Higher
IHC4
Lower
Higher risk
MammaPrint
Low
High
Tumor DNA ploidy
Mostly diploid
Mostly aneuploid
St Gallen 2017
11
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