207_Combined course Presentations
Phase III trials – Investigating Oxaliplatin
Fluoropyrimidine Platform
Trial
Eligibility
CAO/ARO/AIO-04 <12cm from anal verge
5FU 1000mg/2 X 5 days 1-5 + 29-33
T3/T4 cN0/N+ TRUS, CT and/or MRI
NSABP R04 N=1606
<12cm; resectable stage II, III TRUS or MRI – CT if T4/ N1-2
PVI 5FU vs Capecitabine
FFCD N=598
Palpable; resectable; T3/4 N0-2; T2 distal anterior
Capecitabine in both arms
STAR – 01 N=747
Resectable stage II, III (c stage) <12cm from anal verge
PVI 5FU in both arms
PETTAC 6 N=1090
Stage II or III resectable or expected to become resectable <12cm from anal verge
Capecitabine in both arms
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