207_Combined course Presentations
CAO/ARO/AIO-04 Trial
Primary Endpoint DFS Median Follow-up: 50 months (range: 0.3-73) Time between randomisation and the first of the following events: Incomplete local resection (R2) Locoregional recurrence after R0/R1 resection (+/- distant metastases)
5-FU arm n=623
5FU/OX arm n=613
10
5
23 (3.7%)
12 (2%)
Distant metastases / Progression
149
115
Death
Overall Cancer / treatment related/surgical mortality
106 69/4/6 26 1
96 54/7/4 31 0
Unrelated Unknown
First events for DFS (total)
198
159
Ref: Adapted from Rodel et al, ASCO 2014
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