207_Combined course Presentations

DAHANCA 10 randomized phase III

Recruitment and number of patients

Estimated gain: 12% in loco-regional control. (Alpha 0.05, beta 0.2, 5-year hazard rate: 80%) Needed number of events: 282 Estimated number of patients: 600 Start June 1, 2002. Estimated recruitment time: 3 years (200 pts/year). Planned interim analysis after 150 events.

Overgaard et al ICHNO 2013