207_Combined course Presentations
ADXS11-001 immunotherapy
• live attenuated Listeria monocytogenes (Lm) • bioengineered to secrete a HPV-16-E7 fusion protein targeting HPV transformed cells.
• Anal cancer cells infected with HPV have the tumour associated antigen HPV E7.
• So ADXS11-001 causes antigen presenting cells to be stimulated to facilitate immune cells to attach to cancer cells expressing HPV E7
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