207_Combined course Presentations

TMZ + “short-course” RT in Elderly: New standard regimen ?

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Newly diagnosed Glioblastoma

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Patients 65 years of age or older (median age 73)

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RT dose: 40 Gy/15 fractions

Concurrent TMZ: 75 mg/m 2 /day for 21 consecutive days

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Adjuvant TMZ: 150-200 mg/m 2 /day for 5 consecutive days out of 28 for up to 12 cycles or until progression

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Perry JR et al, NEJM 2017;376