207_Combined course Presentations

Annals Oncol. 2007;18

Neurotoxicity: the big problem…

 WBRT ± chemotherapy is associated with more pronounced cognitive impairment than chemotherapy alone

 Long term impairment in the areas of attention, executive function, memory and psychomotor speed

>60 years

 High incidence of neurotoxicity particulary in patients > 60 years

<60 years