207_Combined course Presentations

Toxicity profile of ”reduced dose” WBRT

WHITE MATTER CHANGES (Fazekas scale)

 At baseline, five of 12 patients had grade ≥ 2 white matter disease, which decreased to one of 12 after chemotherapy.

 At the 4-year evaluation, the proportion of patients with white matter changes increased:

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G2 changes  5 patients G3 changes  3 patients G4-G5 changes  0 patients

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Morris PG et. al JCO 2013;31