207_Combined course Presentations

Neuropsycological tests

ASCT WBRT

p= 0.001

Attention/execution

p= 0.001

p= 0.001

Attention/execution

p= 0.001

Attention/execution

Motor

 A significant impairment of some attention/executive functions among patients treated with WBRT was recorded , while results of tests addressing language and memory were stable after this therapy .

 Patients treated with ASCT exhibited improved functions at most of the performed test, and both consolidation therapies were associated with improved QoL figures.

 BUT… 2 toxic deaths (out of 40 patients, 5%) in the arm of Consolidative ASCT.

Ferreri AJM. et al. Blood; abstract book ASH 2016