207_Combined course Presentations
Enrichment and patient selection
Element
Challenges
Solutions
Molecular selection
Central screening •
Activate molecular screening programs national based or locally supported using validated multiplexed assays (funding remain an issue)
Archived tumor samples requested
Return of molecular information
•
Turnaround time variable
•
Local screening •
Local screening not reimbursed
Assay may not be validated in CLIA lab
•
Identification of rare subset of patients
Screening costs while number of eligible patients with financial challenges to keep many trial open with less patients recruited
Support for screening Multiplexed screening Umbrella or basket protocols
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