31 Uveal Melanoma

Uveal Melanoma

7

THE GEC ESTROHANDBOOKOF BRACHYTHERAPY | Part II Clinical Practice Version 1 - 15/04/2020

TABLE 4 AJCC CLASSIFICATION OF POSTERIOR UVEAL MELANOMA (CHOROIDAL AND CILIARY BODY), STAGING When T is... And N is... And M is... Then the stage group is T1a NO MO I T1b-d NO MO IIA T2a NO MO IIA T2b NO MO IIB T3a NO MO IIB T2c-d NO MO IIIA T3b-c NO MO IIIA T4a NO MO IIIA T3d NO MO IIIB T4b-c NO MO IIIB T4d-e NO MO IIIC Any T N1 MO IV Any T N1 M1a-c IV

TABLE 5 AJCC CLASSIFICATION OF POSTERIOR UVEAL MELANOMA (CHOROIDAL AND CILIARY BODY), HISTOLOGIC GRADE G Category G Criteria

GX

Grade cannot be assessed

G1

Spindle cell melanoma (>90% spindle cells)

G2

Mixed cell melanoma (>10% epithelioid cells and <90% spindle cells

G3

Epithelioid cell melanoma (>90% epithelioid cells)

TABLE 1, 2, 3, 4, 5: Adapted from Amin MB, Edge SB, Greene F, et al., eds.: AJCC Cancer Staging Manual. 8th ed. New York, NY: Springer, 2017, pp 805–17 (ref 80)

Fig. 4: US A scan / the tumour thickness is the distance between Peak A (right arrow) and Peak B (left arrow)

Fig. 2: Fondus oculi with tumour

Fig. 5: GTV and CTV definition based on fundus oculi and eye section

Fig. 3: US B scan / Red line: diameter – Blue line: thickness

Fig. 6: GTV definition based on ultrasound exam (B scan on the left and A scan on the right)