7th ICHNO Abstract book

7th ICHNO 7 th ICHNO Conference International Conference on innovative approaches in Head and Neck Oncology 14 – 16 March 2019 Barcelona, Spain __________________________________________________________________________________________ page 29

PO-054 Adaptive radiotherapy in head and neck cancers; Which patient group needs to be prioritised ? M. Figen 1 , D. Colpan Oksuz 2 , E. Duman 3 , R. Prestwich 4 , K. Dyker 4 , K. Cardale 4 , V. Ramasamy 4 , P. Murray 4 , M. Sen 4 1 Sisli Hamidiye Etfal Training and Research Hospital, Radiation Oncology, İstanbul, Turkey; 2 Istanbul University Cerrahpasa Faculty of Medicine, Radiation Oncology, Istanbul, Turkey; 3 Antalya Training and Research Hospital, Radiation Oncology, Antalya, Turkey; 4 Leeds Cancer Centre, Clinical Oncology, Leeds, United Kingdom Purpose or Objective Adaptive radiotherapy in head and neck cancers may increase effectiveness by ensuring target coverage and by improving sparing organs at risk. However there is an ongoing debate about implementation of adaptive radiotherapy as part of routine practice. The aim of this retrospective study is to analyse the patients treated in 2016 who required ad hoc replanning and identify factors which may predict need for replanning. Material and Methods A single centre service evaluation of all patients receiving radical or post-operative (chemo) radiotherapy with the diagnosis of head and neck squamous cell carcinoma (HNSCC) between January 2016 and December 2016. All radiotherapy technical treatment details reviewed and patients who underwent replanning after commencing treatment were identified in the MOSAIQ system. Reasons of re-planning were reviewed and categorized as: weight loss, tumor shrinkage, changes in patient position, immobization-related factors. These factors were correlated with 15 patient related characteristics including age, gender, Karnofsky performance status scale (KPS), primary site, tumor/nodal staging, overall stage, concomitant chemotherapy, induction chemotherapy, weight and BMI scales, weight loss ratios, radical/adjuvant treatment and feeding interventions. Results A total of 290 HNSCC patients were identified. 31 (%10.6) underwent replanning due to weight loss, tumor shrinkage, changes in position or mask related reasons. The most common reason for planning was tumor shrinkage in 11/31 (35%) and weight loss 11/31 (35%). There was no difference between the replanned/no replan groups in distribution of gender, age, weight loss ratios, BMI and pre-treatment/end-of-treatment weight, KPS, gastrostomy or nasogastric tube use, T and N stages, overall stage, adjuvant or radical status, inducton chemotherapy status, concomitant chemotherapy regimen. Amongst the 6 nasopharyngeal carcinoma patients 3 were replanning and this was the only factor significantly correlated (p=0.013). Conclusion Unscheduled ad hoc replanned was common. Clinical factors mainly fail to predict which patients require replanning. Effective on-treatment verification schedules remain critical to identifying patients requiring replanning to ensure target coverage/adequate OAR sparing. PO-055 Interfractional brachial plexus movement during radical radiotherapy in Head and Neck cancer A. Sarwar 1 , A. Thompson 1 , S. English 1 1 North Middlesex Hospital, Radiotherapy Department, London, United Kingdom Purpose or Objective Treatment volumes for radical radiotherapy to head and neck cancers commonly extend into the lower neck, the territory of the brachial plexus (BP). There is a risk of

Conclusion This survey concluded that NPC is the most commonly observed HNC in Chinese clinical practice. Further, the treatment practices of Chinese oncologists were in line with NCC guidelines and recommended ICT along with targeted therapy for HNC management.