7th ICHNO Abstract book

7th ICHNO 7 th ICHNO Conference International Conference on innovative approaches in Head and Neck Oncology 14 – 16 March 2019 Barcelona, Spain __________________________________________________________________________________________ page 73

the Head and Neck has a negative effect on social, recreational, and sexual functioning. These unmet needs of patients influence partially or completely their psychological wellbeing. To resolve the ‘satisfaction paradox’, well-rehearsed psychological tools need to be used. Material and Methods This study evaluates the psychological status of patients in follow-up. We used two scales for this study, the first is EORTC QLQ-30 (n=170) and the second is Hospital Anxiety & Depression (n=100) assessed by a skilled interviewer. The subjects were head and neck cancer patients coming for regular follow-up who were disease free. A total number of 270 patients were assessed in which 170 were with EORTC scale and 100 with HAD scale. Results Within HAD two psychological problems were assessed - Anxiety and Depression. For Quality of Life EORTC QLQ-30 was used, which had three divisions- (a) General condition (b) Physical condition (c) Social condition. QLQ-30 scale was used for 170 patients in which 89%(n=145) were males and 11% were females. Patients with bad general condition were 18%, physical condition were 28% and social condition were 41%. Same patients were administered for HAD. Patients who scored not normal on (a) depression scale were 45% (n=45) and on (b) anxiety scale were 55% (n=55). Conclusion The QoL is used to evaluate the general wellbeing of the patient, With high scores on QoL-30. HAD scale is used to evaluate the psychological aspect of mental wellbeing. This study focuses to evaluate the QOL and the psychological issues separately in follow up cases of head & neck cancer. Further, analysis should be encouraged to re-align patients’ personal, social, family & economical health at large. PO-138 Prognostic value of tailored nutritional support in Head and Neck cancer patients undergoing treatments L. Tondulli 1 , I. Trestini 1 , L. Carbognin 2 , I. Sperduti 3 , C. Bonaiuto 1 , S. Pilotto 1 , G. Tortora 4 , M. Milella 1 , E. Bria 4 1 Azianda Ospedaliera Universitaria Integrata, Department of encology, Verona, Italy ; 2 Università Cattolica del Sacro Cuore- Fondazione Policlinico Universitario ‘A. Gemelli’ I.R.C.C.S., Division of Gynecologic Oncology- Department of Woman and Child Health, Rome, Italy ; 3 Regina Elena National Cancer Institute, Biostatistics, Rome, Italy; 4 Università Cattolica del Sacro Cuore- Fondazione Policlinico Universitario ‘A. Gemelli’I.R.C.C.S., Department of Oncology, Rome, Italy Purpose or Objective Patients affected by Head and Neck Cancer (HNC) experiment a high risk of malnutrition, with an unintentional weight loss and several nutritional challenges at time of diagnosis, during and after the end of treatments. This study aims to evaluate the prognostic role of personalized nutritional intervention in HNC patients undergoing chemotherapy and/or radiotherapy. Material and Methods Data from patients affected by HNC (stage II-IV) diagnosed between April 2010 and August 2016 at the AOUI of Verona and undergoing chemotherapy and/or radiotherapy were retrospectively analyzed. Descriptive statistics was adopted. Clinical, pathological and nutritional data were correlated with Overall Survival (OS) using a Cox model.

Results The final population was made of 87 patients. Forty-one patients (47.1%) received a tailored nutritional intervention, including personalized dietary counseling by a skilled dietitian, in addition to oral nutritional supplements, according to spontaneous food intake and tolerance, and 46 patients (52.9%) did not receive that, without a significant difference for baseline characteristics. At the multivariate analysis, independent significant predictors of better outcome (OS) were the response or stable disease after the first line treatment (HR 4.62, p<0.0001 ), the Performance Status <1 (HR 2.06, p=0.037 ), the nutritional intervention (HR 3.72, p<0.0001 ), and the BMI ≥25 at baseline (HR 2.85, p=0.006 ). Especially, the 3-year OS was 59.0% in patients receiving the nutritional support and 34.9% in patients who did not receive that ( p=0.007 ). Among patients with unplanned hospital admissions ³2 (37 pts [42.5%]), the nutritional intervention significantly discriminated the OS (61.5% vs. 25.5%, p=0.006). Conclusion This study supports the prognostic relevance of the integration of tailored nutritional support into the overall management of HNC patients undergoing chemotherapy and/or radiotherapy. PO-139 Second Primary Cancer in Salivary gland cancer: A Nationwide Population-based Study J. Heo 1 , Y. Oh 1 , O.K. Noh 1 , M. Chun 1 , C. Kim 1 , Y.S. Shin 1 1 Ajou University School of Medicine, Radiation Oncology, Suwon, Korea Republic of Purpose or Objective The aim of this study was to evaluate the prevalence of second primary cancer (SPC) among salivary gland cancer (SGC) patients by using nationwide claims data in South Korea. Material and Methods The nationwide cohort assessed in this study patients who were diagnosed with SGC from January 1, 2010, to December 31, 2014. We analyzed cancer incidence according to the time sequence. Additionally, we evaluated standardized incidence ratios (SIRs) to estimate the risk of SPC in SGC patients. Results A total of 1,614 patients (868 male and 746 female subjects) who were diagnosed with SGC and received surgery were confirmed. Of these patients, one-hundred and fifty-five patients (9.6%) developed an SPC, and the most common cancer site was the thyroid (13.5%). Patients with SGC had a high risk of SPC (SIR 4.39, 95% CI: 3.73 – 5.14), particularly nasopharynx cancer (SIR 79.43), Non-Hodgkin lymphoma (SIR 14.95) and tonsillar cancer (SIR 66.67). Female had a higher risk of malignancy than male (SIR 5.14 for women and SIR 3.73 for men). Conclusion SGC patients with surgery had a longer life expectancy and a higher risk of SPC than the general population did. Therefore, close surveillance for SPC is important in patients with SGC. PO-140 Psychiatric comorbidities among tongue cancer in South Korea: A nationwide population-based study J. Heo 1 , Y. Oh 1 , O.K. Noh 1 , M. Chun 1 , C. Kim 1 , Y.S. Shin 1 1 Ajou University School of Medicine, Radiation Oncology, Suwon, Korea Republic of