ESTRO 2020 Abstract book

S624 ESTRO 2020

ypT2 after TEM refused major surgery. All pts are alive without disease. 44 (72.3%) pts achieved a CR: 22 underwent conservative approach (9 TEM and 13 W&S) and 22 ones TME surgery. Within 3 years from diagnosis, 4 (9.09%) pts who underwent conservative approach presented local recurrence and therefore underwent LE and 4 (9.09%) developed distant metastases (mainly hepatic). All pts are alive with stable disease. Overall, pts underwent surgery obtained a pCR, ypT2-3 and ypN+ in 8, 11 and 3 cases, respectively. All patients are alive without disease, except for one patient who died of senescence. Among the patients who underwent surgical treatment, 23 (47%) of them obtained a correspondence between ycT and ypT . Table 2 reported correlation between clinical and pathological response.