ESTRO 2020 Abstract book

S726 ESTRO 2020

PO-1287 Quality of life (QL) in elderly breast cancer survivors. Effects of surgery. Global QL determinants J.I. Arraras 1 , A. Manterola 1 , J.J. Illarramendi 2 , G. Asin 1 , M. Campo 1 , S. De la Cruz 2 , U. Zarandona 1 , B. Ibañez 3 , M. Rico 1 , E. Salgado 2 , M.A. Dominguez 1 , M. Barrado 1 , E. Martinez 1 1 Complejo Hospitalario de Navarra, Radiotherapeutic Oncology, Pamplona, Spain ; 2 Complejo Hospitalario de Purpose or Objective Quality of Life (QL) is a key target of the attention that is offered to elderly breast cancer patients survivors. The aims of the present study are to assess QL in a sample of elderly early-stage breast cancer survivors; to study QL differences based on clinical variables; and to identify Global QL determinants. Material and Methods A consecutive sample of stages I-III elderly breast cancer patients who had received treatment at the Oncology Departments of the Complejo Hospitalario de Navarra was invited to participate in the study. Patients were > 65 years old at the study entry and have had a follow up period of at least 5 years after surgery. They might have received adjuvant radio, chemo and / or hormotherapy. They had no relapse. Patients filed in once the EORTC QLQ-C30 (general QL), QLQBR45 (breast specific QL) and QLQ-ELD14 (elderly specific QL) questionnaires. Demographic and clinical data were recorded. QL differences between groups based on breast surgery (conservative – mastectomy) and presence of limiting comorbidity were studied (Wilcoxon tests). Univariate and multivariate logistic regression analyses were performed to identify demographic, clinical and QL areas related to low global QL (≤50 points considered low global-QL score). Results 277 patients filled in the questionnaires. 132 patients (48%) had limiting comorbidity. Karnofsky mean(sd) score in the first assessment was 81(9.2). 228 patients (83%) received endocrine treatment. QL scores were high in most areas (>80/100 points functioning, <20 points in symptoms areas) with moderate limitations (>30 points) in worries about others, maintaining purpose, joint stiffness (elderly specific); sexual functioning and enjoyment (breast specific); and light limitations (20-30 points) in emotional functioning, sleep disturbance, fatigue, pain, global QL (general QL); future worries and breast satisfaction (breast specific); and future perspective and family support (elderly specific) areas. Patients with limiting comorbidity showed lower QL in eight general areas, seven breast specific and four elderly specific QL areas. There was no difference in any area between breast surgery groups. Performance status, age, comorbidity, eleven general, ten breast and seven elderly areas had a statistically significant relationship with low global QL. Fatigue and Endocrine Therapy Symptoms showed the highest R2 (0.38). The best model to explain low global QL included, as explanatory variables, high fatigue, worries about others and endocrine therapy symptoms as risk factors (R2 = 0.60) Conclusion Elderly early-stage breast cancer patients adapted well both to their disease and treatments over the follow-up period. Comorbidity has a key role in their QL, whereas QL did not differ between surgery-treated groups. Fatigue, endocrine secondary effects, and worries about others have a key role in QL in elderly breast cancer patients Navarra, Medical Oncology, Pamplona, Spain ; 3 Navarrabiomed-CHN-UPNA. IdisNA. REDISSEC, Methodology Unit, Pamplona, Spain

did not: 41.0% vs 35.0% (p<0.001), 36.0% vs 26.0% (p<0.001) and 39.0% vs 32.0% (p=0.292) for MO, RO and SO, respectively. Conclusion Gender disparity exists in academic MO, RO and SO faculty, which is magnified at the leadership level. Programs with a female physician in a leadership position were associated with a higher percentage of female faculty. This data will serve as a benchmark to monitor progress towards a more balanced workforce. PO-1286 An update from the 1st ESTRO-CARO-RANZCR course on Foundations of Leadership in Radiation Oncology. T. Basu 1 1 HCG Cancer Centre, Radiation Oncology, Mumbai, India Purpose or Objective The 1 st ESTRO-CARO-RANZCR course on “Foundations of Leadership in Radiation Oncology (FLRO)” was introduced to bring about the leadership qualities among the young oncologist specifically dealing with radiotherapy. The report gives an overview from one of the participants highlighting the need, benefit and future directions. Material and Methods The FLRO course started with advertisement in ESTRO website and a motivation letter, short resume and competitive application were required. The course as planned had online presence through interactive webinars and on-site training and interaction at ESTRO-37 held at Barcelona between 20 th -22nd april, 2018. The last part of webinar is scheduled in mid-June 2018. Before the beginning of the course the reading materials were uploaded in ESTRO website through a separate application only to the selected applicants. The onsite 3 days course started with full day session on day 1 and two lunch symposiums on consecutive days afterwards. The onsite sessions had didactic lectures, interactive sessions among participants, short task sessions, designing a project with fellow participants and also engaging games bringing out real world problems related to young leadership issues. Results The course started with webinar and questionnaires through survey monkey analysing each participant’s personality. The onsite training at Barcelona within the framework of ESTRO annual congress remained quiet engaging. The 1 st day morning session started with six participants in each table and each introduced the person next to them and that really broke the ice. Afterwards the personality trait analysis with red, blue, green and yellow color coding and highlighting the strength and weakness of each persona from your opposite trait followed by circle forming between introvert and extrovert was extremely engaging. Personality analysis through the PMH module really brought about the real character. The second day lunch symposium had different set of people to interact and each had to present their pre-assigned short project to two other fellow colleagues for constructive inputs. The third and last day lunch symposium with another set of people were asked to design a short project on improving radiotherapy care and present in front of audience in disguise as fellow radiation oncologist, stakeholders, policy makers and general public. The highly interactive format was the biggest strength of the course with participation across globe. There was another survey after the onsite course and participation certificate was sent via email. Conclusion Participants across the globe face the similar challenge of introducing novelty among stakeholders. The inherent nature of each personality with their strength and weaknesses also plays a vital role. Future longer duration course with some educational grant support aiming at real world projects and probably on-site project will bring about real world young leaders in radiation oncology.