AROI-ESTRO GYN Teaching Course

Limitations of the EQD2 model for BT

 Chemotherapy is not taken into account

 Uncertainty increases for single fraction dose values >10Gy

 Only cell repair is considered

 / values and T

1/2 are under discussion (E.g. tumour type prostate, OAR etc.)

 Overall uncertainty of the biological dose calculation (values) in the range of ~10% -> Reasonable rounding of values

BT-GYN Teaching Course

D. Berger