AROI-ESTRO GYN Teaching Course

Step 4: Defining MRI based (adaptive) Volumes and Doses • ICRU 38 Revision Report committee (1999-2016) • Gyn GEC ESTRO Working group/network (2001-….) • ABS Recommendations : (2005-2014) GYN GEC ESTRO recommendations I (Haie-Meder t al.) - contouring GYN GEC ESTRO recommendations II (Pötter et al.) - dose vol. parameters GYN GEC ESTRO recommendatio s III Hellebust et al.) - reconstruction GYN GEC ESTRO recommendations IV (Dimopoulos et al.) - imaging ABS recommendations n GYN ge eral (Viswanathan and Th madsen, ABS Cervical Cancer Recommendations Committee) - general ABS recommendations on GYN HDR (Viswanathan et al.) ABS recommendations on GYN PDR (Lee et al.) • Concept of Volume and Dose specification volumetric GTV, (adaptive) CTV, OARs residual GTV, CTV HR and CTV IR , D 90 , D 100 fixed absolute volumes for OAR, D 0.1cm3 • Biological modelling: equi-effective dose (EQD2) 2cm3 , D

assessing different doses per fraction/dose rates for GTV res , CTV HR , CTV IR , OAR