AROI-ESTRO GYN Teaching Course

S ize of the tumor at Brachytherapy

Volume change during treatment

Regression to P roportional V olume: PV = V x / V 1 [%]

N= 115

BT

EBRT

stage IB2 - IVA

V

V

V

V

2

4

1

3

PV = 100 %

PV = 87 %

PV = 31 %

PV = 40 %

100

•Rapid response: 2.2% / Gy •Steep slope •Low AUC (24 %) •Slow response: 0.8% / Gy •Low slope •High AUC (50 %)

Alive & well at 7 y

80

60

40

LR at 1 y Death at 2 y

20

Proportional Volume [%}

0

1

2

3

4

Mayr NA, et al. Int J Radiat Oncol Biol Phys 2010