AROI-ESTRO GYN Teaching Course

TUMOR REGRESSION DURING EXTERNAL RADIATION THERAPY

• Significant changes in tumor volumes occur during EBRT • Tumors shrink & often quite quickly with CTRT • Shrinkage is a double-edged sword

 University of Utah used physical exam measurements and found by 30.8 Gy tumors reduced by 50%  MD Anderson used weekly conventional CT & noted a mean reduction of 64%

Lee et al. Red Journal 2005;58:625 Beadle et al. ASTRO 2006

Mayr et al. Am J Roentgenol 2006;187:65 Van de Bunt et al. Red Journal 2006;64:189