ASMR

Margins for small leasions hypo fractionated

Adding up some/al the errors:

Delineation uncertainty

2 mm

Residual set up error after imaging (2D or 3D) • bone registration

0.5 mm 0.6 mm 0.6 mm

• soft tissue changes

Intrafraction motion

PTV margin = 2.5 Σ + 0.7 σ

1mm margin/ 0mm margin??

Literature show excellent local controle!