ATP 2016

22113 – 08113 Trial design

Expert review 1: Staging

Eligibility confirmation will be sent via email to the site

Upload of images on EORTC Imaging platform

Central Review Step 2 registration Expert review 2: Eligibility for RT

RTQA Central Review: delineation and treatment planning

Treatment plan confirmation will be sent via email to the site

RTQA Central Review (retrospective): treatment verification CBCT Upload on EORTC Radiotherapy platform

Histological/Cytologic al confirmation of NSCLC Staging with CT + FDG-PET/CT

Upload on EORTC Radiotherapy platform

4D-CT RT planning – using 3D FDG- PET/CT co-matching

Image guided SBRT with CBCT verification 7.5 Gy*8 fr = 60 Gy

CT scans (+ FDG-PET/CT or biopsy if required)

ORTA - Step 1 registration Informed Consent

Follow-up

Treatment

3 monthly visits for the first 3 yrs, 6 monthly for the 4-5 yrs, and yearly until the end of the trial

Maximum 6 weeks from date of FDG-PET/CT to start of SBRT

18

Adebahr et al ,BJR /2015