ATP 2016

Extreme breast hypofractionation – preoperative single-dose PBI

Ongoing Phase II studies

1. Duke University 1x21 Gy • in prone position • breast-conserving surgery at 6 weeks after RT

2. UMC Utrecht 1x20 / 15 Gy • in supine position •

breast-conserving surgery at 6 months after RT • Primary endpoint: pathological complete response

Horton IJROBP 2015, Charaghvandi RO 2015