ATP Barcelona 2017

Dosimetry, Biology and Clinic

• Dosimetry: planning related data  Dose distribution  Fractionation  Volume irradiated  Hot-Cold spots  DVH (and related indicators) • Biology: OAR  Dose/Response models (Lyman, Log-Logistic…)

V-values D-values Mean dose

Maximum dose Minimum dose

Volume effect

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Reliability of radiobiological prediction • Clinic: factors that can affect the outcome  Patient related: Age, Smoke, HPV status (for H&N), comorbidities…  Treatment related: chemo, hormonal therapy…  Prognosis, treatment aim (definitive, local control, palliation)