ATP Barcelona 2017

Equivalent Uniform Dose

 The EUD is base on the assumption that two dose distributions are equivalent if they produce the same radiobiological or clinical effect (end-point)  D j : the dose in the volum bin  v j : volum bin  a : parameter that describes the serial/parallel structure of the organ

a 1

j    =  = 1

  

a j Dv

EUD

j

Niemierko A. A Concept of Equivalent Uniform Dose (EUD). Volume & Kinetics in Tumor Control & Normal Tissue Complications. 5 th International Conference on Dose, Time and Fractionation in Radiation Oncology. 1998