ATP Barcelona 2017

Individual variation in normal tissue sensitivity

• Variation in response harder to observe with mega-voltage beams because of skin sparing

• Could be exploited: 

To avoid toxicity in sensitive patients  ≤ 5% of patients

To dose escalate resistant patients  40% of patients - dose escalate up to ~15%



• Other methods to measure normal tissue response are needed, to produce more & better dose response data