Abstract Book

S911

ESTRO 37

and recalsification effect in MM patients and has curative treatment role in SP patients. We aim to evaluate the results of RT to pain relief, recalsification and local control in PCT. Material and Methods Between January 2005 and December 2016, totally 89 patients with osteolitic bone lesion confirmed by radiology were included. Zoledronic asit treatment was added with median 4 months period to all patients. Pathologic fracture was recorded in 20 (22.5%) patients and surgical stabilization was performed to 16 (18%) cases. Treatment fields were determined by considering the involved bone characteristics. RT applied by using 6 MV Lineer Accelerators. Total doses were 45 Gy with 1,8 Gy per fraction for SP and 30 Gy with 2,5-3 Gy per fraction for MM.Treated osteolitic lesion was controlled after 6 months to RT in terms of radiologic recalsification response. Characteristic Number (%) Gender FemaleMale 36 (40,4%)53 (59,6%)

assess the efficacy of a weekly resident study group in improving understanding of clinical site management, preparation for the radiation oncology program exam, and confidence in clinical management skills. The logic model was also used to assess the program organization and efficiency. Material and Methods The resident study group was assessed using the logic model for program evaluation. A study schedule was developed by the chief resident to allow for coverage of all major clinical sites prior to the December in-house exam. Twelve weekly, hour-long sessions were planned from July 31 to December 15, 2017. Data extraction and analysis occurred after six sessions. An anonymized survey using the Jotform platform was generated, with questions based on literature review results of logic- model based theories of evaluation. Survey questions pertained to program activities, resources used, short- term outcomes, and early stages of long-term outcomes. Residents could indicate on each survey element whether they found it to be excellent, very good, fair, poor or very poor. Results The study group overall was found to be excellent by half of the residents. The content was described as very good by 67% of the residents. Half of the residents felt the study sessions improving their confidence towards the in- house exam. The majority of residents felt the organization of the course was excellent (50%) and very good (33%). Use of landmark papers was mostly fair (33%). Adherence to the study schedule was mostly good (50%). The amount of clinical radiation oncology learned was described as very good to good by 66%. A weekly schedule was described as excellent to very good by 50% of the radiation oncology residents. Meeting time at 8 am was described to be excellent to very good by 34% of the residents. Efficient utilization of time was agreed to by 84% of the participants. Half of the residents studied 2-4 hours per week while 17% studied 0-2 hours per week. Preparation for the study group sessions was 0-2 hours and 2-4 hours for 67% and 17% of the residents respectively. Conclusion The radiation oncology resident study group is effective in working towards the goals of the program. About half of the participants felt the course improved their confidence in preparing for the December in-house exam. The majority of participants felt the organization of the program to be excellent to very good. Most of the residents studied 2-4 hours per week for clinical radiation oncology, with about 0-2 hours dedicated to preparing for the resident study group. Therefore, a significant portion of study efforts revolved around study group material. However, there are areas for program improvement, such as utilization of landmark papers. EP-1698 The Pain Relief and Recalsification Results of Radiotherapy in Plasma Cell Tumors F. Sert 1 , S. Kamer 1 , G. Saydam 2 , M. Argın 3 , Y. Anacak 1 1 Ege University, Department of Radiation Oncology, Izmir, Turkey 2 Ege University, Department of Hematology, Izmir, Turkey 3 Ege University, Department of Radiology, Izmir, Turkey Purpose or Objective Plasma Cell Tumors (PCT) contains multiple myeloma (MM) and solitary plasmasitoma (SP).Radiotherapy (RT) has an important role in terms of obtaining pain relief

Age at diagnosis Median (year)

57 (range, 36-88)

Stage Solitary

Plazmasitoma

11

(12,4%)

Multipl Myeloma

78 (87,6%)

Irradiated Vertebra Pelvis Extremity

bone

45 10 14

(50,6%) (11,2%) (15,7%) (5,6%) (5,6%)

bone

Scalp Costal

5 5

bone

ScapulaClavicula

2 (2,2%)8 (9,0%)

Results Serious and intermediate pain were recorded 20 (22.5%) and 64 (71.9%) patients, respectively.Complete and partial pain response were experienced in 65 (73%) and 17 (19.1%) patients,respectively. Any type of recalsification response was obtained in 86 (96.7%) patients.Complete and partial radiologic recalsification response was recorded in 45 (50.6%) and 41 (46.1%) patients, respectively. Of the patients who had complete response radiologically, 9 (81.8%) were SP and 36 (46.1%) were MM (p=.025). The major difference was total RT dose between these two groups. When the radiologic recalsification response was evaluated in terms of total radiation dose, complete response was significantly higher in total 45 Gy RT doses than 30 Gy doses (p<.001). Local control was obtained in 82 (92.1%) patients. 7 (7.9%) patients experienced disease progression during the follow-up and times to local progression were 7, 9, 11, 12, 72, 84 and 119 months. In median 23 months follow-up period, 2-year local control rate for whole group, SP and MM were 94%, 100% and 93%, respectively (p=.384). Conclusion RT has an important role in PCTs for obtaining pain relief, preventing pathologic fractures and reducing analgesic intake. Additionally, remodulation in bones may be considered as a secondary but long term goal for radiotherapy. Our data showed that adequate pain relief and recalsification effects could be supplied with minimum 30 Gy total doses and one should wait minimum 6 months for the recalsification response to RT. Our trial is important in terms of using objective methods for both pain relief and recalsification response.