Advanced Brachytherapy Physics - Vienna 2016

Application variation in fractionated HDR GYN BT (Kirisits et al. 2006)

Mean differences between single plan for all implantations to individual plan for each implantation 5 9 G f D CTV . y or 90 HR (14 % for BT dose only, 7 % including EBRT)

Much higher compared to interfraction study: BT applied already during EBRT! (shrinkage)