Advanced Brachytherapy Physics - Vienna 2016

Increasing OAR dose constraints by reducing uncertainties

20%

 D=5 Gy

30%

10%

Same complication rate predicted for SD 30% @ 70 Gy EQD2 SD 20% @ 75 Gy EQD2

Clinician could consider relaxing the OAR dose constraint for this case, if it were possible to decrease large random uncertainties in the workflow! “Can reduction of uncertainties in cervix cancer brachytherapy potentially improve clinical outcome?” Nesvacil et al. 2016, submitted to R&O