Advanced Brachytherapy Physics - Vienna 2016

Deformable registration

• Problem: fusing images (from different modalities), taken at different times in the treatment (before, during, after BT) I) Some organs move and change shape dramatically (sigmoid), II) insertion of applicator changes topography, … Approximation by rigid registration fails. • Aim: to register each voxel correctly with the corresponding voxel in a different image set in order to evaluate the received radiation dose . • Currently, especially for the pelvic region and breast it is theoretically not solved how tissue voxels can move, expand and shrink.