Advanced Physics for Brachytherapy 2018

Dose planning and reporting for 3D image based APBI (GEC-ESTRO trial)

Major et al. 2007, Radiother Oncol 90(1):48-55

PTV: excision cavity + 20mm safety margin

Results for 28 pts. (mean and ranges): volume PTV:

63.1cm³ (17.2-124cm³) 102 % (99-107 %)

D D

PTV:

90

PTV::

69 % (90-96 %)

100

DNR:

0.33 (0.25-0.41)

D

skin

skin D

:

53 % (18-75 %)

max

max

≥5mm

ipsilateral lung D

: 42 % (7-75 %)

max

heart

V5Gy: 42.6 cm³ (0-160 cm³) V10Gy: 4.8 cm³ (0-39.5 cm³) V15Gy: 0.5 cm³ (0-7.9 cm³) 21 % (4-40 %) V5Gy: 8 cm³ (0-33.5 cm³) V10Gy: 0.1 cm³ (0-0.3 cm³)

lung

planning aim: PD = 30.1Gy (7x 4.3Gy), V 100 = 90%, DNR <0.35, implant-rib distance ≥ 5mm

heart D

:

max