Advanced Physics for Brachytherapy 2018

Inverse Optimisation and Planning

Objectives & Objective Functions

Define Dose Window for Target(s), NT & OAR(s)

Objective Functions

Objectives

1

Low-Objective D L for V Low

=

෍ =1

Θ −

−

1

High-Objective D H for V High

=

෍ =1

Θ −

−

d i

j is the Dose at the Sampling Point j for Objective Function i :

+∞

~

k ASDP

N

N

i

i jkl lkK lk

2

  = cath k 1

d

d Sx

= (x)

Ԧ = න

´

− ´

j

,

l

=

1

−∞

Implanted Catheters

Active SDPs

Dwell time t

= x

²

lk

lk