Advanced Physics for Brachytherapy 2018

A short Introduction into the Multiobjective Optimisation Problem

Facts

Inverse Optimisation and Planning for brachytherapy has to consider several Objectives and is thus a Multiobjective ( MO ) problem. We have competing Objectives . Increasing the dose in the Target will increase the dose outside it. A trade-off between the Objectives exist and we never have a situation in which all the Objectives can be in the best possible way satisfied simultaneously.

1

(low)

GTVs CTV/PTV OARs NT

=

෍ =1

Θ −

−

1

(high)

=

෍ =1

Θ −

−