Advanced Physics for Brachytherapy 2018

Inverse Optimisation and Planning: A Multi-Objective (MO) Problem

Trade-off between three objectives (objective functions) for a prostate implant:

f 1 : PTV coverage , f 2

: urethra overdose and f 3

: rectum overdose .

There resulting three two-dimensional projections are shown. These show the trade-off between two objectives in each case. While for two objectives a solution very close to the optimal can be found, this becomes more difficult as more objectives are considered. The complexity of the Pareto Front increases rapidly with the number of objectives / objective functions .